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Safe NAD

Cell survival, human trials and the meaning of safe.

About Safe NAD

About Safe NAD and NAD+

“Safe” is the question that started this site. A molecule essential to cells deserves a more exact discussion than a reassuring adjective.

Repair and growth

The awkward overlap between repair and growth intrigues me. Cells need NAD+ for essential work, yet the consequences of helping cells depend on their condition. The mouse liver transporter experiment makes that complexity wonderfully difficult to brush aside.

Safe NAD is an editorial website about published NAD+ research. I want room for promising findings without giving an essential molecule automatic credit for every intervention bearing its name. The human clinical-evidence review leaves plenty to investigate.

Medical questions

Safe NAD provides no clinical care, medical consultations or treatment. There is no product shop or appointment service behind the name. Nothing on these pages is personal medical advice.

Scrutiny of a study cannot assess a reader's symptoms, medical history or suitability for an intervention. Those decisions require a qualified health professional who can do that assessment.

The possibility of helping a damaged cell while also supporting unwanted growth denies me the comfort of a favourite answer. A safety claim needs to specify the cells, the preparation and the observation period it concerns. Enthusiasm about repair and anxiety about cancer can each outrun the evidence. I would rather live with an unresolved question than force these different findings into one reassuring verdict. An answer confined to side effects would feel incomplete. So would an answer confined to mechanisms. Safety has to meet a person eventually, with all the complications that a controlled experiment holds still.

The reading list collects the research. The correspondence page sets out the scope for factual corrections.